What is the the best for the globalization of server, severals instance or one instance and severals database on one server ?I would use separate instances if I had separate "processes" that critically can not be impacted by th other. One instance can fail, while the others remain unaffected.
That said, I have not seen 2000 fail over the last 2 years.
It really depends on what you are doing and what your server looks like.
For example, many large web presences have several servers where the data is replicated across to each.
What are you trying to do?
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